Chromosome Absolutism’s Last Stand: La Scap’s War on Biology

X’s Chromosome Crusaders: Sophistry Masquerading as Science

X (formerly Twitter) is a battleground for social-media “experts” peddling chromosome determinism with ruthless zeal. Leading the charge is “La Scap,” a self-styled gender-critical voice who insists a Y chromosome alone locks in maleness—genetics, fetal development, and anomalies be damned.

Biologist Colin Wright, in Avoid the “Intersex Trap”, traces this tactic to sophistry: the ancient Greek art of persuasion over truth. Sophists twisted facts to win crowds; today, La Scap twists biology to win arguments. She’s flipped Wright’s lens—once aimed at intersex activists—onto her own camp, wielding chromosome absolutism like a blunt axe. Gene function, hormone pathways, and Disorders of Sex Development (DSDs)? Irrelevant noise to her.

La Scap’s Own Words Betray Her.

Her X post lays out the contradiction:

She nods to complexity—mosaicism, chimerism, a dud SRY gene on the Y—then snaps back: “Only two sexes.” A fertile XXY female? “Unique,” she shrugs, swept aside. Exceptions don’t refine her rule; they’re roadkill. Her noble motive—keeping men out of women’s spaces—stumbles when she calls a mother “male” to dodge her own logic’s cracks.

Chromosomes vs. Reality

La Scap preaches: XX or XY dictates sex—end of story. Biology begs to differ:

• SRY and Fetal Development: The Y’s SRY gene typically triggers testes and male hormones (MedlinePlus Genetics). If it fails—even with XY—ovaries can form. Sex hinges on SRY’s action, not just a Y on the chart.

• Hormones and Receptors: In Complete Androgen Insensitivity Syndrome (CAIS), XY individuals with testes but no testosterone response develop as phenotypic females (GeneReviews). Chromosomes scream “male”; bodies ignore them.

• Chromosomal Twists: Klinefelter (47,XXY) usually trends male with a working SRY, but quirks—fertility issues, softer traits—tag along. If SRY flops, female development can dominate. La Scap dismisses it as “rare” yet clings to her dogma.

The XXY Female and XX Male Paradox

Her hard line snares her. She cites a fertile 47,XXY female—“severe Y impairment,” still “male” by her metric. Science counters: if SRY tanks, XXY can yield ovaries and kids (Röttger et al.). Then there’s XX male syndrome—male anatomy, no Y. By her rule, they’re “female.” An XY Swyer woman who births kids? “Male.” An XX man with a penis? “Female.” Her escape from one trap lands her in another, making her stance sound unhinged—crazier than the gender ideologues she fights.

Mosaicism: The “In-Between” She Can’t Tame

She admits mosaicism and chimerism—XX and XY cells in one body—can yield ovotestes or ambiguous anatomy. Yet she rejects “in-between sexes,” claiming it props up her “two-sex” wall. It’s a dodge. Science doesn’t peddle a “third sex”; it reveals chromosomal chaos blurs the binary (Ghervan et al.). Her fixation can’t wrestle that reality into submission.

The Human Cost

I live this. Born with congenital hypogonadotropic hypogonadism (HH)—no puberty, stunted anatomy, infertility etched in—DSDs like mine are pawns in a war we didn’t sign up for. Gender ideologues fetishize us as props; chromosome zealots like La Scap erase our lived sex. Her 36K-follower echo chamber distorts reality with real fallout:

• Misguided Choices: Parents of DSD kids—like Klinefelter cases—might swallow her “chromosomes rule” line, delaying critical care.

• Muddied Waters: She buries genes, hormones, and development under false certainty.

• Erased Lives: HH mimics Lupron’s effects—a puberty blocker I fight to spare kids from. I couldn’t start puberty; blockers stole it from others. DSDs bring infertility, underdeveloped bodies, and mental strain. La Scap’s crusade fuels stigma while ideologues parade us as trophies.

Sophistry’s Sleight of Hand

Her playbook is textbook sophistry:

1. Set the rule: “Chromosomes decide. Two sexes, no exceptions.”

2. Nod to glitches: “Sure, a fertile XXY female—an odd fluke.”

3. Hold the line: “Still male by karyotype.”

It’s a slick dance—concede, then smother. She keeps the sheen of rigor, but her concession guts her case: if SRY or hormones fail, chromosomes don’t reign.

Conclusion: Development Trumps Dogma

Biology doesn’t bow to La Scap’s chromosome fetish. XX=female, XY=male works for most, but fetal development—SRY’s function, hormone flows—can rewrite the script. Her own slip—“female fertility in a male with 47 XXY”—lays bare the flaw. To save her theory, she calls a mother “male.” It’s not science; it’s contortion. Comparing DSD folks to men needing uterus transplants is as absurd as equating a fish to a submarine.

Honest science owns the rule and the exceptions. Chromosomes start the game; genes and development finish it. La Scap’s noble aim—a firm male-female line—crumbles under her contradictions, leaving DSD people like me as collateral damage in her rhetorical crossfire.

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References

• MedlinePlus Genetics. “SRY Gene (Sex Determining Region Y).” Genetics Home Reference, U.S. National Library of Medicine, https://medlineplus.gov/genetics/gene/sry/.

• “Androgen Insensitivity Syndrome.” GeneReviews, NCBI Bookshelf, https://www.ncbi.nlm.nih.gov/books/NBK1429/.

• MedlinePlus Genetics. “Klinefelter Syndrome.” Genetics Home Reference, U.S. National Library of Medicine, https://medlineplus.gov/genetics/condition/klinefelter-syndrome/.

• Röttger, S., et al. “An SRY-Negative 47,XXY Mother and Daughter.” Cytogenetic and Cell Genetics, vol. 91, no. 1-4, 2000, pp. 204–207, https://pubmed.ncbi.nlm.nih.gov/11025456/.

• Ghervan, C., et al. “A Rare Case of Ovotesticular DSD by 46XX/46XY Chimerism.” Endocrine Abstracts, vol. 73, 2021, AEP576, https://www.endocrine-abstracts.org/ea/0073/ea0073aep576.

• Ahmad, R., et al. “46,XX Ovotesticular Disorder of Sex Development (True Hermaphroditism) with Seminoma: A Case Report.” Medicine, vol. 99, no. 41, 2020, e22557, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589703/.

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About the Author

James Linehan holds a master’s degree and has taught as an adjunct lecturer. He works in AI, specializing in large language models, and lives with congenital hypogonadotropic hypogonadism—a DSD that halted his puberty, leaving infertility and underdeveloped anatomy. Starting HRT at 16 to treat his CHH, he advocates against puberty blockers’ permanent toll on kids.